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BPC 157 administration raises several questions regarding its therapeutic role in the process occurring in rats with obstructed vessels (Sikiric et al., 2014

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The evidence breaks down into distinct tiers, and this article doesn't blur them together: Preclinical/animal research: substantial for both peptides individually, not for the combination Controlled human trials: none completed (Phase 2 or 3) for either compound, for any indication, as of this writing Uncontrolled human reports: one small report is sometimes cited describing symptom improvement in a subset of chronic knee-pain patients after a single BPC-157 injection - a different evidence class from a controlled trial Anecdotal patient reports: real-world telehealth users describe perceived benefit for injury recovery