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The first reaction, resulting in succinic acid semialdehyde (SSA), is catalyzed by GABA transaminase (GABA-T or GABA-AT, encoded by ABAT gene) that belongs to class-III of PLP-dependent aminotransferase family and exists in the form of a homodimer [179]

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It is derived from the HGH amino acid sequence 176–191 and was designed to retain the hormone’s fat-metabolising properties while avoiding its growth-promoting and blood sugar–altering effects (1)