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Trimethylamine is subsequently converted into TMAO by flavin-containing monooxygenases in the liver

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[29] Considering that the total estimated number of new cancer diagnoses (all types of cancer) is 1,958,310, this means bone sarcomas represent only 0.2% of all new cancer diagnoses (making them the 30th most common type of cancer [28] ) and soft-tissue sarcomas represent only 0.7% (making them the 22nd most common type of cancer [30] ) of all new cancer diagnoses in the US in 2023