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In injection form, higher concentrations can occasionally trigger mild gastrointestinal symptoms, nausea, loose stools, or a feeling of stomach heaviness, in people who are sensitive to it or who are new to the formula

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Siméon y colaboradores (2000) encontraron en fibroblastos dérmicos un aumento de MMP-2, la metaloproteinasa ligada al recambio de matriz, acompañado de mayor secreción de TIMP-1 y TIMP-2, que son sus reguladores