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They used population pharmacokinetic/pharmacodynamic (PK/PD) modeling to analyze tesofensine and its metabolite, as well as cognitive assessment scale data from 62 mild AD patients in placebo-controlled studies

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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Hong S, Moreno-Navarrete JM, Wei X, Kikukawa Y, Tzameli I, Prasad D, Lee Y, Asara JM, Fernandez-Real JM, Maratos-Flier E, Pissios P