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Plasma GHK declines with age, from about 200 ng/mL at age 20 to about 80 ng/mL at 60 (Pickart and Margolina, 2018), which is one reason women look at it for skin and hair

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In this scenario, choosing a compounded version with b12 added costs only slightly more than compounded semaglutide alone, making the combination potentially worthwhile even without clear medical necessity