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Note, the cytoprotection concept made by Robert (prevention of stomach epithelial cell necrosis) [41,42,43,44] and Szabo (endothelium protection) [45,46,47,48,49,50] links the original protection of stomach epithelial cells to the protection of other organs (organoprotection) [42,47] (i.e., for eye pharmacotherapy, stomach epithelium behaves like eye epithelium [15]), and stomach-cytoprotective agents to agents with pleiotropic beneficial effect [42,47]

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We generally don't recommend switching routes mid-cycle because the dosing isn't directly comparable