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[11] [4] Preclinical studies have suggested that combining amylin receptor agonism with GLP-1–based therapies produces greater reductions in food intake and body weight than either approach in isolation, and early clinical data from the CagriSema programme (cagrilintide combined with semaglutide) has provided some supporting evidence in humans

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It is speculated that DSIP may shorten the onset of sleep and enhance sleep quality by modulating the activity of several neurotransmitters in the brain

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